MuriPhys supports preclinical liver research relevant to Wilson’s disease, hemochromatosis and familial hypercholesterolemia. Connect the disease model and delivery route with the biochemical, tissue, metabolic or functional measurements needed for the study.
By partnering with MuriPhys, you leverage specialized technology and scientific expertise designed to accelerate the development of groundbreaking therapies for liver disorders.
Liver Diseases We Specialize In:
Wilson’s disease research can combine oral gavage, IV or IP administration with appropriate tissue and biochemical measurements. Copper-related endpoints and chelation questions require suitable analytical methods. Metabolic or imaging readouts can complement the study where relevant. Wilson’s Disease Read More.
Hemochromatosis research can examine iron-related biology and treatment responses using IV, IP or oral administration. Iron and organ-related endpoints require appropriate analytical or tissue methods. Rotarod, open-field, treadmill and metabolic monitoring can add defined functional readouts when relevant.
Familial hypercholesterolemia research can incorporate viral-vector or other test articles with IV, SC or IP delivery. Lipid measurements and cardiovascular endpoints require suitable assays. Imaging, rotarod and metabolic monitoring can complement the study when they address a defined question.
Why MuriPhys for Liver Disease Research?
- Drug Delivery: Select oral gavage, IV, IP or another appropriate route with the formulation, exposure question and model in view.
- Metabolic and Behavioral Analysis: Our metabolic chambers and behavioral tests provide in-depth assessments of systemic health, motor function, and metabolic performance, critical for evaluating liver disease progression and treatment outcomes.
- Advanced Imaging Capabilities: specialized imaging tools allow non-invasive monitoring of liver health, biodistribution and therapeutic response.
- Tailored Research Programs: MuriPhys customizes every aspect of liver disease studies to reflect the specific pathophysiology and therapeutic targets, providing focused insight into disease mechanisms and treatment efficacy.