Ataxia studies can use delivery to the cerebellar cortex and deep cerebellar nuclei, or study-appropriate ICV, IT and ICM routes. MuriPhys uses Neurostar robotic stereotaxy for micrometer-scale instrument positioning. Anatomical targeting, test-article suitability and reproducibility are assessed with study-specific planning and quality controls.
Ataxia is a neurological condition characterized by a lack of voluntary coordination of muscle movements, leading to problems with gait, balance, and other motor functions. It can affect various parts of the body and primarily result from cerebellar or spinal damage/dysfunction.
To complement our CNS delivery MuriPhys offers behavioral tests and in vivo electrophysiology that assess selected disease-relevant features, including:
