In Vivo Study Planner

Step 1 of 6

Study outline

Start with the question. You can leave details open for discussion.

Study nameWhat is this study for?Primary research areaAnimal species

Study lead, reference & funding (optional)

Client study lead / investigatorYour study reference

Funding source / program

What do you need to learn?

More context or an existing study outline

Other indications or platform focus

Paste a nonconfidential outline

Step 2 of 6

Animals & model

Define the model and groups without guessing what you do not know.

Model & readiness

Choose what you know. A named model is a request to discuss feasibility and readiness, not a confirmed study protocol.

Model approachModel, strain or cell line

Model requirements or relevant disease stage

Study timing & housing

Record housing from arrival through the final animal collection, including recovery and study time.

Standard acclimation is 5 days. Animals from unapproved sources may require quarantine. MuriPhys confirms source approval and any additional quarantine time before arrival.

Model establishment / recovery (days)Study period after recovery (days)Total housing from arrival (days)Who provides / purchases the animals?Animal source / vendorAnimal source approvalHousing arrangementProposed animals per cage, if known

Housing, staggered arrivals & cohort requirements

Experimental groups

Add each treatment, comparator or terminal cohort separately. Leave animal numbers blank if you would like help planning them.

Study rigor & additional timing notes

Study duration after recovery / inductionRecovery / model establishment period

Primary outcome and assessment time

Allocation / randomizationBlinding / masking

How will animal numbers be justified?Why this species and model?Planned comparisons & statistical analysisSex, group split and rationaleMonitoring, recovery & humane endpointsNAMs & the 3Rs

Step 3 of 6

Treatment plan

Connect the test article, administration approach and schedule.

Test articles & administration

Add an entry for each test article, combination or administration approach. Enter proposed doses only if you have them.

Step 4 of 6

In-life measures

Choose the readouts that will make the result useful.

What would you like to measure?

Select an assessment to open its frequency, number of sessions and animal-count fields directly below it. Specialist methods and imaging are confirmed for the project.

Other in-life observations or requirements

Step 5 of 6

Samples & outputs

Plan sample collection, analysis and the information you need back.

Serial samples

Select a sample type to open its collection frequency, time points, animal numbers and specimen counts.

Overall collection plan / shared blood drawsBlood collection method, if known

Terminal collection & brain microdissection

Specify the tissues, regions and processing needed for the downstream readouts.

Other tissues or collection requirements

Brain regions for microdissection

Other regions or substructures

Animals for terminal collection

Processing / storage

Analysis & deliverables

Select an analysis to specify the matrices, specimen counts, analytes, assay readiness and sample sourcing for that service.

Overall analysis coordination & sample allocation

ReportingProtocol support

Protocol or documentation requirements

Complementary cell-based work & NAMs

Connect suitable non-animal evidence with this in vivo plan. Model relevance, method readiness and scope are reviewed together.

Additional scientific & facility support

Timing & other requirements

Preferred start / deadlineWho will execute the work?

Anything else the team should know?

Step 6 of 6

Review & send

Check the outline, save a copy and send it to our team for pricing.

Scoping details for review

These quantities, schedules and sourcing details help our team prepare a comparable scope. You can send an unfinished plan for discussion.

Your study-plan document

Questions to resolve with our scientists